Software abstracts
Marc Lavielle SAEM in MATLAB: an alternative to linearization
Posters Thursday (group I)
1. Anthe Zandvliet Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine poster as zipped pdf
5. Sophie Gisbert Different approaches to the development of a WBPBPK model with a series of barbiturates using population modelling
7. Kayode Ogungbenro The Design of Population Pharmacokinetic Studies: Sample Size Determination
9. Thorsten Lehr Clock time as a control variable for gall bladder emptying in an enterohepatic circulation model poster as pdf
11. Elaine Blair Pharmacokinetic-Pharmacodynamic Modelling of Raltitrexed in Patients with Advanced Solid Tumours
13. Holger Kraiczi Effect of Uncertainty About Population Parameters on Pharmacodynamics-Based Prediction of Clinical Trial Power - A Method for Sensitivity Analysis poster as pdf
15. Bart Ploeger The reversal of rocuronium-induced neuromuscular block by the cyclodextrin ORG25969: model development and validation poster as pdf
17. Teun Post A Mechanistic Disease Progression Model for Type 2 Diabetes Mellitus and Pioglitazone Treatment Effects poster as pdf
19. Mike Smith A Bayesian design and analysis for dose-response using informative prior information poster as pdf
21. Elspeth Lamont Population Pharmacokinetics of Teicoplanin in Outpatient Home Parenteral Antibiotic Therapy (OHPAT) poster as pdf
23. Matthew Zierhut Development and Evaluation of a Population PK/PD Model for Fc-OPG in Healthy Postmenopausal Women poster as zipped pdf
25. Aris Dokoumetzidis Propagation of population pharmacokinetic information using a Bayesian approach poster as pdf
27. Marc Pfister Characterization of Cortisol Circadian Rhythm and Lack of Cortisol Suppression by a New Corticosteroid, Ciclesonide poster as pdf
29. Vladimir Piotrovsky Population pharmacokinetic analysis of concentration data after implantation of sirolimus-eluting Bx Velocity stent in patients poster as pdf
31. Karl-Heinz Liesenfeld Population pharmacokinetics of a new anticoagulant drug in clinical development poster as pdf
33. Jean-Eric Charoin Population Pharmacokinetic Analysis of Trastuzumab (Herceptin) following Long-Term Administration Using Different Regimens poster as pdf
35. Jeff Barrett Esmolol Population Pharmacokinetics in Critically-ill, Pediatric Patients poster as pdf
37. Jakob Ribbing Learning about Covariate Relations in the Patient Population Based on Data from Multiple Studies – Consequences of Different Approaches poster as pdf
39. Lena Friberg Simultaneous fit of competing models as a model discrimination tool in Bayesian analysis poster as pdf
41. Hugo Maas Comparison of sumatriptan and naratriptan using a markov model approach poster as pdf
43. Francesco Fiorentini An example of application of the population approach to toxicological studies poster as ppt
45. Annick Rousseau Modeling the complex pharmacokinetic profiles of cyclosporin and of mycophenolate observed in the early post-transplantation period poster as pdf
47. An Vermeulen Modeling the occurrence of orthostasis using a longitudinal logistic regression model
49. Brian Mc Hugh Population PK and PK/PD Analyses of an Enzyme Inhibitor in Healthy Volunteers poster as pdf
51. Lia Liefaard Application of Population Pharmacokinetic Analysis for Quantification of in vivo Binding Properties in the Rat Brain by Positron Emission Tomography poster as pdf
53. Willi Weber Comparing efficacy of 10mg vs 20mg ARAVA in treatment of rheumatoid arthritis: A Population PK / PD Analysis poster as pdf
55. Rune Overgaard Non-Linear Mixed Effects Models with Stochastic Differential Equations - Implementation of an Estimation Algorithm poster as pdf
57. John Lukas The cytochrome P450 3AP1 variant genotype shows correlation with the true clearance in a renal transplant population poster as pdf
Posters Friday (group II)
2. Daniel Jonker Development and validation of a mechanism-based PK/PD model for the in vitro-in vivo prediction of QT prolongation by dofetilide poster as pdf
4. Monica Simeoni Population modeling of tumor growth inhibition in vivo: application to anticancer drug development poster as pdf
6. Xuejun Chen Population Pharmacodynamic Analysis of QTc Prolongation vs. Plasma Concentration
8. Michael Dodds A Population PK Model for Recombinant Factor XIII in Healthy Volunteers
10. Florence Hourcade-Potelleret Population PK Analysis in Sparse Data and Flexible Sampling Time Conditions poster as pdf
12. Emmanuelle Comets Cerebral uptake of mefloquine enantiomers with and without theP-gp inhibitor elacridar (GF1210918) in mice poster as pdf
14. Kristin Cecilie Carlsson Can clinically useful population PK models for carbamazepine in pediatric epilepsy patients be developed based on routine therapeutic drug monitoring (TDM) data? poster as pdf
16. Sandra Visser Modeling of drug- and system-related changes in body temperature: application to drug-induced hypothermia, long-lasting tolerance development and diurnal variation in body temperature poster as pdf
18. Bernard Vrijens Identifying and minimizing major sources of variability in population pharmacokinetic studies poster as pdf
20. Lutz Harnisch A Population PK/PD Model for Cortisol Suppression
22. Karl Brendel Comparison of several prediction errors on concentrations for model evaluation poster as ppt
24. Michael Dodds Robust Population Pharmacokinetic Experiment Design
26. Klaas Zuideveld Quantification of 5-HT7 receptor efficacy distribution throughout the canine stomach using the operational model of agonism.
28. Nils Ove Hoem A non-parametric (NPAG) population PK model of orally and intravenously administered linezolid.
30. Andrew Hooker Evaluating the predictive power of the Fisher information matrix in population optimal experimental design poster as pdf
32. Sylvie Retout Comparison between the Fedorov-Wynn algorithm and the Simplex algorithm for population designs optimisation using a model of the HIV viral load decrease
34. Marta Valle Population pharmacokinetic/pharmacodynamic modeling of the possible tolerance development after a single oral dose of different BZD-GABAa agonists.
36. Maria Kjellsson Fitting Proportional Odds model to Ordered Categorical Data using the NLMIXED Procedure poster as pdf
38. Onintza Sayar Beristain Comparison of different models to describe simultaneously the kinetics of parent drug and metabolites after oral administration poster as zipped pdf
40. Niels Rode Kristensen A Deconvolution Method for Linear and Nonlinear Systems based on Stochastic Differential Equations poster as pdf
42. Dymphy Huntjens Population semi-parametric modelling of the pharmacokinetics of rofecoxib in rats poster as pdf
44. Italo Poggesi Population modeling of tumor growth in untreated xenografted mice poster as pdf
46. Maria Garrido Modelling of the effect of Topotecan on B cell subsets in tumor bearing rats poster as zipped pdf
48. Lars Lindbom PsN Toolkit, a collection of computer intensive methods for population PK/PD
50. Justin Wilkins A population pharmacokinetic-enzyme model for rifampicin autoinduction and bimodal absorption in pulmonary tuberculosis patients poster as pdf
52. Carl Kirkpatrick Population pharmacokinetic analysis of high-dose oral busulphan for bone marrow transplant in adults and children poster as pdf
54. Hanna Silber A disease model for the regulation of the glucose-insulin system poster as pdf
56. Claire Ambery Population Pharmacokinetics and Response of ICL670 a Novel Oral Iron Chelator in Beta-Thalassaemia Patients poster as pdf
