1999 - Saintes - France

Thursday June 17
08:00-08:40	Registration and coffee
08:40-09:00	Welcome and Introduction
	Oral session I	PK/PD modelling	chair: Rik Schoemaker
09:00-09:35	Janet Wade	Combining PK and PD data during population PK/PD analysis
09:35-10:00	Mats Karlsson	A pharmacodynamic Markov mixed effect model for temazepam effect on sleep
10:00-11:30	Poster and software session I
	Oral session II	Non-parametric methods	chair: Christian Pobel
11:30-12:10	Alain Mallet	Non-parametric methods for continuous and binary data variables in population PK/PD
12:10-12:30	Roger Jelliffe	Population PK/PD modelling and optimal drug dosage
12:30-14:00	Lunch
	Oral session III	Trial design	chair: France Mentre
14:00-14:35	Byron Jones	Constructing optimal designs for fitting pharmacokinetic models
14:35-15:10	Mick Looby	Dose-response in early drug development
15:10-15:45	Michel Tod	Robust optimal design for population parameters
15:45-16:45	Poster and software session II
	Oral session IV	Clinical applications	chair: Leon Aarons
16:45-17:05	Gilles Freyer	Population pharmacokinetic parameters of doxorubicin, ifosfamide and etoposide in small cell lung cancer patients
17:05-17:25	Stephen Dufful	Development of a linked pharmacokinetic and pharmacodynamic simulation model for ivabradine in healthy volunteers
17:25-17:45	Sylvie Chabaud	Use of a therapeutic model for simulating phase III clinical trials of a new bradycardic agent
17:45-17:55	Pascal Girard	PAGE discussion
19:45- open	Social event	about 5 minutes from hotels by coaches
Friday June 18
	Oral session V		chair: Pascal Girard
09:00-09:45	Anthony Davison	Bootstrap methods
09:45-10:05	Ulrika Wählby	Determination of inclusion frequency of false covariate relationships in population modelling
10:05-10:25	Per Olsson Giselskog	The use of priors in NONMEM analysis
10:25-11:55	Poster and software session III
	Oral session VI		chair: Janet Wade
11:55-12:30	Peter Milligan	Viagra
12:30-13:05	Barry Jones	Pharmacogenetics
13:05-13:25	Niclas Jonsson	Quantifying non-standard evidence for drug approval
13:25-13:45	Roberto Gomeni	Population analysis (NONMEM) using a concentration-to-event approach to evaluate the propofol anaesthesia induction strategy using a TCI system
13:45-14:00	Closure followed by light lunch