Peregrina-Lucano A.A.1,2, Martín-Suárez A.1, García L.R.2, González M.H.2, Garcia M.J.1, Lanao J.M.1 Comparative study of NONMEM and WinNonMix in the population pharmacokinetics of benznidazol
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Eugène Cox, Eric Snoeck & Jaap Mandema Population pharmacodynamic model for count data: Application to clinical trial simulations for compound PH2000 for the improvement of the number of satisfying events.
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Frey, N., Laveille, C. and Jochemsen, R. Effect of Quinidine on the Pharmacokinetics and Pharmacodynamics of a CYP2D6 substrate (S-YYYY) via mixed-effect modelling
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Oscar Della Pasqua and Alan Maloney When baseline matters. The presence of bias and inaccuracy in population parameter estimates derived from
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John C. Lukas1, George L. Drusano2, Paolo Vicini1 Comparison of covariate models for Bayesian posterior pharmacokinetic parameter estimates from NONMEM with those from a n onparametric approach: Application to levofloxacin.
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C. Della Pepa, M. Costa#, R. Canaparo, L. Serpe, GP. Zara, F. Casale, E. Berno and M. Eandi. Analysis Of 5-Fu And Three Metabolites Concentration In Plasma Cancer Patients By Bayesian Autoclassificatio N Method.
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Willi Weber, Lutz Harnisch Learnings from a Population Pharmacokinetic Substudy of a Large Phase III Trial
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J. A. Simpson1,2, R. Price1,3, F. ter Kuile3,4, P. Teja-Isavatharm5, F. Nosten1,2,3, T. Chongsuphajaisiddhi2, S. Looareesuwan2, L. Aarons5, N. J. White1,2 Population Pharmacokinetics of Mefloquine in patients with acute falciparum malaria
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Michael Becka An approach to non-linear kinetics using first-order characteristics
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Michael Becka An approach to non-linear kinetics using first-order characteristics
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C Terret, E Erdociain, R Guimbaud, T Lafont, R Bugat, P Canal, E Chatelut Inter- and intra-patient variabilities of Michaelis-Menten parameters of 5-fluorouracil
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Georg Hempel 1,2, Nina Griese1,2, Petra Schulze Westhoff1, Dirk Reinhardt1, Ursula Creutzig1 and Joachim Boos1 Pharmacokinetics of Daunorubicin after Application of Liposomal Daunorubicin (Daunoxome®) in Children
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Y.Merlé(1) and M. Tod(2) Impact Of Model Linearization On The Accuracy Of Population Information Matrix And Optimal Design
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Valle M, Drover D, Angst M, Verotta D. Semi-Parametric Approach To Describe Hydromorphone Plasma Concentrations After The Administration Of Immediate And Controlled-Release Formulations
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Emmanuelle Comets (1), France Mentré (1), Ryosei Kawai (2), Peter Marbach (2) and Jacky Vonderscher (2). Evaluation of tests based on individual versus population modelling to compare dissolution curves
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Vladimir K. Piotrovsky, Achiel Van Peer Cardiovascular Safety Data Analysis via Mixed-Effects Modelling
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Vladimir K. Piotrovsky, Achiel Van Peer Separating Responders and Non-responders Using A Mixture of Distributions: An Example of Count Response
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M.J. Garrido1, M van den Haak, M Danhof and P-H van der Graaf2 Population Pharmacokinetics of the Low-Efficacy Opioid receptor Agonists: Butorphanol and Nalbuphine
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Mangues MA1, Trocóniz IF2, Soy D3, Alba G1, García M1, Ginovart G4. Population Pharmacokinetics of Gentamicin in Neonates
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Ho-Nguyen T.X.Q1., Girard P2.,Chabaud S2., Munafo A1. Population pharmacokinetic analysis of recombinant human Chorionic Gonadotrophin (Ovidrel) compared with that of urinary human Chorionic Gonadotrophin (Profasi) in women undergoing superovulation
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Ulrika Wählby, E. Niclas Jonsson and Mats O. Karlsson Assessment of actual significance levels for covariate model building using NONMEM
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G. Graham1, I. Nestorov1, L. Aarons2 Application Of Optimal Design For Categorical Pharmacodynamic Measures In Clinical Trials.
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E Capparelli, J Connor, J Lane, Ja Englund, P Palumbo, C Baker and PAGTG 152 Team. Population Pharmacokinetics and Pharmacodynamics of Zidovudine HIV Infected Infants and Children
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J.A. Dowell, Ph.D., S.P. King, Ph.D., H.Liu, Ph.D., M.S. Berger, M.D., and J.M. Korth-Bradley, Pharm.D., Ph.D. A Population Pharmacokinetic Analysis Of A New Antibody Chemotherapeutic Agent: Gemtuzumab Ozogamicin.
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Roger W. Jelliffe1 and David S. Bayard2 An Interactive Multiple Model (Imm) Estimation Approach To Updating Posteriors In Pharmocokinetic Models Having Changing Parameter Values
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S. Jönsson* and M.O. Karlsson A Strategy For Selection Of Dose Sizes And Dosing Algorithm Based On A Real Data Example
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R.A.A. Mathôt1, R.P.G. van Heeswijk1, H.J. Scherpbier2, L.A. de Koning3, H.S.A. Heymans2, J.M.A. Lange3, J.H. Beijnen1, R.M.W. Hoetelmans1 Population Pharmacokinetics Of Nelfinavir In HIV-1-Infected Children
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Charlotte van Kesteren1, Ron A.A. Mathôt1, Luis López-Lázaro2, Esteban Cvitkovic3, Jose M. Jimeno2, Jos H. Beijnen1 Population pharmacokinetics of the novel marine derived anti-cancer agent Ecteinascidin 743 in a phase I study using non-linear mixed effects modelling.
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R.A.J.Wixley Use of Phase I PK/PD results in design and analysis of Clinical trials with Sparse data
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Ken-ichi Sako , Kimikazu Shinozaki Application of population approach to TDM services and educational programs
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E. Niclas Jonsson, Lars Lindbom, Jakob Ribbing and Mats O. Karlsson Perl-speaks-NONMEM (PsN) - a perl library of support functions for NONMEM related programming.
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M. de Hoog1,2,, A.A.T.M.M. Vinks4, R.C. Schoemaker2,3, J.N. van den Anker1,2 Pharmacokinetic modeling of tobramycin in neonates: a comparison of NONMEM and NPEM2
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Pérez-Ruixo, JJ; Casabó, VG; Merino, M; Llopis, MC; Jiménez, NV. Population Pharmacokinetic And Pharmacodynamic Of Cyclophosphamide In Breast Cancer.
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Martín-Suárez A1, Falcao AC2, Outeda M 3, Mora F4, González MC5, Quero M5, Arranz I4, Lanao JM1 Kinetic behaviour of digoxin in a paediatric population
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LJ Van Obbergh, A Robert, F Veyckemans, F Roelants, RK Verbeeck. Population Pharmacokinetics Of Ropivacaine Injected Caudally In Infants And Children
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